İHALE DÜNYASI
İHALE DÜNYASI
Each Anusol-HC (R) 25 mg Suppository contains 25 mg hydrocortisone acetate in a hydrogenated vegetable oil base. Hydrocortisone acetate is a corticosteroid. Chemically, hydrocortisone acetate is pregn-4-ene-3, 20-dione, 21-(acetyloxy)-11, 17-dihydroxy (11?)- with the following structural formula: Structural Formula
For use in inflamed hemorrhoids, post-irradiation (factitial) proctitis, as an adjunct in the treatment of chronic ulcerative colitis, cryptitis, other inflammatory conditions of the anorectum, and pruritus ani.
Usual Dosage: One suppository in the rectum morning and night for two weeks, in nonspecific proctitis. In more severe cases, one suppository three times daily; or two suppositories twice daily. In factitial proctitis, recommended therapy is six to eight weeks or less, according to response.
CONTRAINDICATION Anusol-HC (R) suppositories are contraindicated in those patients with a history of hypersensitivity to any of the components.
The following local adverse reactions have been reported with corticosteroid suppositories. 1. Burning 2. Itching 3. Irritation 4. Dryness 5. Folliculitis 6. Hypopigmentation 7. Allergic contact dermatitis 8. Secondary infection To report SUSPECTED ADVERSE REACTIONS, contact Salix Pharmaceuticals at 1-800-321-4576 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch .
